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Microparticles Induce Cell Cycle Arrest Through Redox-Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence

BACKGROUND: Chronic disease accelerates endothelial dysfunction in aging, a process associated with cell senescence. However, the mechanisms underlying this process are unclear. We examined whether endothelial cell (EC)-derived microparticles (MPs) facilitate EC senescence and questioned the role of...

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Detalles Bibliográficos
Autores principales: Burger, Dylan, Kwart, Dylan G., Montezano, Augusto C., Read, Naomi C., Kennedy, Christopher R.J., Thompson, Charlie S., Touyz, Rhian M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487329/
https://www.ncbi.nlm.nih.gov/pubmed/23130145
http://dx.doi.org/10.1161/JAHA.112.001842