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Microparticles Induce Cell Cycle Arrest Through Redox-Sensitive Processes in Endothelial Cells: Implications in Vascular Senescence
BACKGROUND: Chronic disease accelerates endothelial dysfunction in aging, a process associated with cell senescence. However, the mechanisms underlying this process are unclear. We examined whether endothelial cell (EC)-derived microparticles (MPs) facilitate EC senescence and questioned the role of...
Autores principales: | Burger, Dylan, Kwart, Dylan G., Montezano, Augusto C., Read, Naomi C., Kennedy, Christopher R.J., Thompson, Charlie S., Touyz, Rhian M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487329/ https://www.ncbi.nlm.nih.gov/pubmed/23130145 http://dx.doi.org/10.1161/JAHA.112.001842 |
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