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Reduction of Ischemia/Reperfusion Injury With Bendavia, a Mitochondria-Targeting Cytoprotective Peptide
BACKGROUND: Manifestations of reperfusion injury include myocyte death leading to infarction, contractile dysfunction, and vascular injury characterized by the “no-reflow” phenomenon. Mitochondria-produced reactive oxygen species are believed to be centrally involved in each of these aspects of repe...
Autores principales: | Kloner, Robert A., Hale, Sharon L., Dai, Wangde, Gorman, Robert C., Shuto, Takashi, Koomalsingh, Kevin J., Gorman, Joseph H., Sloan, Ruben C., Frasier, Chad R., Watson, Corinne A., Bostian, Phillip A., Kypson, Alan P., Brown, David A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487333/ https://www.ncbi.nlm.nih.gov/pubmed/23130143 http://dx.doi.org/10.1161/JAHA.112.001644 |
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