Diazoxide Maintains Human Myocyte Volume Homeostasis During Stress

BACKGROUND: Exposure to hypothermic hyperkalemic cardioplegia, hyposmotic stress, or metabolic inhibition results in significant animal myocyte swelling (6% to10%) and subsequent reduced contractility (10% to 20%). Both are eliminated by the adenosine triphosphate-sensitive potassium channel opener...

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Detalles Bibliográficos
Autores principales: Maffit, Sara K., Sellitto, Angela D., Al-Dadah, Ashraf S., Schuessler, Richard B., Damiano, Ralph J., Lawton, Jennifer S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487366/
https://www.ncbi.nlm.nih.gov/pubmed/23130119
http://dx.doi.org/10.1161/JAHA.112.000778

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