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LINE-1 Retroelements Complexed and Inhibited by Activation Induced Cytidine Deaminase
LINE-1 (abbreviated L1) is a major class of retroelements in humans and mice. If unrestricted, retroelements accumulate in the cytoplasm and insert their DNA into the host genome, with the potential to cause autoimmune disease and cancer. Retroviruses and other retroelements are inhibited by protein...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487726/ https://www.ncbi.nlm.nih.gov/pubmed/23133680 http://dx.doi.org/10.1371/journal.pone.0049358 |