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Doxorubicin Influences the Expression of Glucosylceramide Synthase in Invasive Ductal Breast Cancer

INTRODUCTION: Glucosylceramide synthase (GCS) is one enzyme that provides a major route for ceramide clearance. Recent evidence has indicated an important role for GCS in multidrug resistance (MDR) tumors. Doxorubicin (DOX)can modulate the expression of GCS in leukemia and ovary cell lines. However,...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaofang, Wu, Xiaojuan, Su, Peng, Gao, Yongsheng, Meng, Bin, Sun, Yanlin, Li, Li, Zhou, Zhiqiang, Zhou, Gengyin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487728/ https://www.ncbi.nlm.nih.gov/pubmed/23133636 http://dx.doi.org/10.1371/journal.pone.0048492

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