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Human Disease Isolates of Serotype M4 and M22 Group A Streptococcus Lack Genes Required for Hyaluronic Acid Capsule Biosynthesis
Group A streptococcus (GAS) causes human pharyngitis and invasive infections and frequently colonizes individuals asymptomatically. Many lines of evidence generated over decades have shown that the hyaluronic acid capsule is a major virulence factor contributing to these infections. While conducting...
Autores principales: | Flores, Anthony R., Jewell, Brittany E., Fittipaldi, Nahuel, Beres, Stephen B., Musser, James M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society of Microbiology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487777/ https://www.ncbi.nlm.nih.gov/pubmed/23131832 http://dx.doi.org/10.1128/mBio.00413-12 |
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