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Caveolin-1 reduces HIV-1 infectivity by restoration of HIV Nef mediated impairment of cholesterol efflux by apoA-I

BACKGROUND: HIV infection results in inhibited cholesterol efflux by apolipoprotein A-I (apoA-I) in macrophages, and this impairment involves Nef mediated down-regulation and redistribution of ATP-binding cassette transporter A1 (ABCA-1). We investigated the effect of caveolin-1 (Cav-1) on the chole...

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Detalles Bibliográficos
Autores principales:	Lin, Shanshan, Nadeau, Peter E, Wang, Xiaomei, Mergia, Ayalew
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487900/ https://www.ncbi.nlm.nih.gov/pubmed/23067370 http://dx.doi.org/10.1186/1742-4690-9-85

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