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Assessment of blinding to treatment allocation in studies of a cannabis-based medicine (Sativex®) in people with multiple sclerosis: a new approach
BACKGROUND: Maintenance of the blind-to-treatment allocation is one of the most important means of avoiding bias in randomised controlled clinical trials. Commonly used methodologies to determine whether patients have become unblinded to treatment allocation are imperfect. This may be of particular...
Autores principales: | Wright, Stephen, Duncombe, Paul, Altman, Douglas G |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487910/ https://www.ncbi.nlm.nih.gov/pubmed/23046749 http://dx.doi.org/10.1186/1745-6215-13-189 |
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