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Disassociation of the SV40 Genome from Capsid Proteins Prior to Nuclear Entry

BACKGROUND: Previously, we demonstrated that input SV40 particles undergo a partial disassembly in the endoplasmic reticulum, which exposes internal capsid proteins VP2 and VP3 to immunostaining. Then, in the cytoplasm, disassembly progresses further to also make the genomic DNA accessible to immune...

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Detalles Bibliográficos
Autores principales: Kuksin, Dmitry, Norkin, Leonard C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487934/
https://www.ncbi.nlm.nih.gov/pubmed/22882793
http://dx.doi.org/10.1186/1743-422X-9-158