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Increased toxicity of a trinuclear Pt-compound in a human squamous carcinoma cell line by polyamine depletion
BACKGROUND: Mononuclear platinum anticancer agents hold a pivotal place in the treatment of many forms of cancers, however, there is a potential to improve response to evade resistance development and toxic side effects. BBR3464 is a promising trinuclear platinum anticancer agent, which is a polyami...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487936/ https://www.ncbi.nlm.nih.gov/pubmed/22640800 http://dx.doi.org/10.1186/1475-2867-12-20 |