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L-citrulline supplementation reverses the impaired airway relaxation in neonatal rats exposed to hyperoxia
BACKGROUND: Hyperoxia is shown to impair airway relaxation via limiting L-arginine bioavailability to nitric oxide synthase (NOS) and reducing NO production as a consequence. L-arginine can also be synthesized by L-citrulline recycling. The role of L-citrulline supplementation was investigated in th...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487946/ https://www.ncbi.nlm.nih.gov/pubmed/22870905 http://dx.doi.org/10.1186/1465-9921-13-68 |