Multi-scale agent-based brain cancer modeling and prediction of TKI treatment response: Incorporating EGFR signaling pathway and angiogenesis

BACKGROUND: The epidermal growth factor receptor (EGFR) signaling pathway and angiogenesis in brain cancer act as an engine for tumor initiation, expansion and response to therapy. Since the existing literature does not have any models that investigate the impact of both angiogenesis and molecular s...

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Detalles Bibliográficos
Autores principales: Sun, Xiaoqiang, Zhang, Le, Tan, Hua, Bao, Jiguang, Strouthos, Costas, Zhou, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Software
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487967/
https://www.ncbi.nlm.nih.gov/pubmed/22935054
http://dx.doi.org/10.1186/1471-2105-13-218

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3487967/
https://www.ncbi.nlm.nih.gov/pubmed/22935054
http://dx.doi.org/10.1186/1471-2105-13-218

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