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Vasculitic emergencies in the intensive care unit: a special focus on cryoglobulinemic vasculitis
Vasculitis is characterized by the infiltration of vessel walls by inflammatory leukocytes with reactive damage and subsequent loss of vessel integrity. The clinical course of systemic vasculitis may be punctuated by acute life-threatening manifestations that require intensive care unit (ICU) admiss...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488028/ https://www.ncbi.nlm.nih.gov/pubmed/22812447 http://dx.doi.org/10.1186/2110-5820-2-31 |
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author | Zaidan, Mohamad Mariotte, Eric Galicier, Lionel Arnulf, Bertrand Meignin, Véronique Vérine, Jérôme Mahr, Alfred Azoulay, Élie |
author_facet | Zaidan, Mohamad Mariotte, Eric Galicier, Lionel Arnulf, Bertrand Meignin, Véronique Vérine, Jérôme Mahr, Alfred Azoulay, Élie |
author_sort | Zaidan, Mohamad |
collection | PubMed |
description | Vasculitis is characterized by the infiltration of vessel walls by inflammatory leukocytes with reactive damage and subsequent loss of vessel integrity. The clinical course of systemic vasculitis may be punctuated by acute life-threatening manifestations that require intensive care unit (ICU) admission. Furthermore, the diagnosis may be established in the ICU after admission for a severe inaugural symptom, mostly acute respiratory failure. Among the systemic vasculitides, cryoglobulinemic vasculitis (CV) has been rarely studied in an ICU setting. Severe CV-related complications may involve the kidneys, lungs, heart, gut, and/or central nervous system. The diagnosis of CV in the ICU may be delayed or completely unrecognized. A high level of suspicion is critical to obtain a timely and accurate diagnosis and to initiate appropriate treatment. We describe severe acute manifestations of CV based on six selected patients admitted to our ICU. That all six patients survived suggests the benefit of prompt ICU admission of patients with severe CV. |
format | Online Article Text |
id | pubmed-3488028 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Springer |
record_format | MEDLINE/PubMed |
spelling | pubmed-34880282012-11-05 Vasculitic emergencies in the intensive care unit: a special focus on cryoglobulinemic vasculitis Zaidan, Mohamad Mariotte, Eric Galicier, Lionel Arnulf, Bertrand Meignin, Véronique Vérine, Jérôme Mahr, Alfred Azoulay, Élie Ann Intensive Care Review Vasculitis is characterized by the infiltration of vessel walls by inflammatory leukocytes with reactive damage and subsequent loss of vessel integrity. The clinical course of systemic vasculitis may be punctuated by acute life-threatening manifestations that require intensive care unit (ICU) admission. Furthermore, the diagnosis may be established in the ICU after admission for a severe inaugural symptom, mostly acute respiratory failure. Among the systemic vasculitides, cryoglobulinemic vasculitis (CV) has been rarely studied in an ICU setting. Severe CV-related complications may involve the kidneys, lungs, heart, gut, and/or central nervous system. The diagnosis of CV in the ICU may be delayed or completely unrecognized. A high level of suspicion is critical to obtain a timely and accurate diagnosis and to initiate appropriate treatment. We describe severe acute manifestations of CV based on six selected patients admitted to our ICU. That all six patients survived suggests the benefit of prompt ICU admission of patients with severe CV. Springer 2012-07-19 /pmc/articles/PMC3488028/ /pubmed/22812447 http://dx.doi.org/10.1186/2110-5820-2-31 Text en Copyright ©2012 Zaidan et al.; licensee Springer. http://creativecommons.org/licenses/by/2.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution License ( http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Zaidan, Mohamad Mariotte, Eric Galicier, Lionel Arnulf, Bertrand Meignin, Véronique Vérine, Jérôme Mahr, Alfred Azoulay, Élie Vasculitic emergencies in the intensive care unit: a special focus on cryoglobulinemic vasculitis |
title | Vasculitic emergencies in the intensive care unit: a special focus on cryoglobulinemic vasculitis |
title_full | Vasculitic emergencies in the intensive care unit: a special focus on cryoglobulinemic vasculitis |
title_fullStr | Vasculitic emergencies in the intensive care unit: a special focus on cryoglobulinemic vasculitis |
title_full_unstemmed | Vasculitic emergencies in the intensive care unit: a special focus on cryoglobulinemic vasculitis |
title_short | Vasculitic emergencies in the intensive care unit: a special focus on cryoglobulinemic vasculitis |
title_sort | vasculitic emergencies in the intensive care unit: a special focus on cryoglobulinemic vasculitis |
topic | Review |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488028/ https://www.ncbi.nlm.nih.gov/pubmed/22812447 http://dx.doi.org/10.1186/2110-5820-2-31 |
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