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Modelling and simulating generic RNA-Seq experiments with the flux simulator
High-throughput sequencing of cDNA libraries constructed from cellular RNA complements (RNA-Seq) naturally provides a digital quantitative measurement for every expressed RNA molecule. Nature, impact and mutual interference of biases in different experimental setups are, however, still poorly unders...
Autores principales: | Griebel, Thasso, Zacher, Benedikt, Ribeca, Paolo, Raineri, Emanuele, Lacroix, Vincent, Guigó, Roderic, Sammeth, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488205/ https://www.ncbi.nlm.nih.gov/pubmed/22962361 http://dx.doi.org/10.1093/nar/gks666 |
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