Discovering the hidden sub-network component in a ranked list of genes or proteins derived from genomic experiments

Genomic experiments (e.g. differential gene expression, single-nucleotide polymorphism association) typically produce ranked list of genes. We present a simple but powerful approach which uses protein–protein interaction data to detect sub-networks within such ranked lists of genes or proteins. We p...

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Detalles Bibliográficos
Autores principales: García-Alonso, Luz, Alonso, Roberto, Vidal, Enrique, Amadoz, Alicia, de María, Alejandro, Minguez, Pablo, Medina, Ignacio, Dopazo, Joaquín
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Methods Online
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488210/
https://www.ncbi.nlm.nih.gov/pubmed/22844098
http://dx.doi.org/10.1093/nar/gks699

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488210/
https://www.ncbi.nlm.nih.gov/pubmed/22844098
http://dx.doi.org/10.1093/nar/gks699

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