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Discovering the hidden sub-network component in a ranked list of genes or proteins derived from genomic experiments
Genomic experiments (e.g. differential gene expression, single-nucleotide polymorphism association) typically produce ranked list of genes. We present a simple but powerful approach which uses protein–protein interaction data to detect sub-networks within such ranked lists of genes or proteins. We p...
Autores principales: | García-Alonso, Luz, Alonso, Roberto, Vidal, Enrique, Amadoz, Alicia, de María, Alejandro, Minguez, Pablo, Medina, Ignacio, Dopazo, Joaquín |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488210/ https://www.ncbi.nlm.nih.gov/pubmed/22844098 http://dx.doi.org/10.1093/nar/gks699 |
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