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Dynamic regulation of HIV-1 mRNA populations analyzed by single-molecule enrichment and long-read sequencing
Alternative RNA splicing greatly expands the repertoire of proteins encoded by genomes. Next-generation sequencing (NGS) is attractive for studying alternative splicing because of the efficiency and low cost per base, but short reads typical of NGS only report mRNA fragments containing one or few sp...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488221/ https://www.ncbi.nlm.nih.gov/pubmed/22923523 http://dx.doi.org/10.1093/nar/gks753 |