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DOT1A-dependent H3K76 methylation is required for replication regulation in Trypanosoma brucei

Cell-cycle progression requires careful regulation to ensure accurate propagation of genetic material to the daughter cells. Although many cell-cycle regulators are evolutionarily conserved in the protozoan parasite Trypanosoma brucei, novel regulatory mechanisms seem to have evolved. Here, we analy...

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Detalles Bibliográficos
Autores principales:	Gassen, Alwine, Brechtefeld, Doris, Schandry, Niklas, Arteaga-Salas, J. Manuel, Israel, Lars, Imhof, Axel, Janzen, Christian J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488242/ https://www.ncbi.nlm.nih.gov/pubmed/22941659 http://dx.doi.org/10.1093/nar/gks801

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