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Nrf2–MafG heterodimers contribute globally to antioxidant and metabolic networks
NF-E2-related factor 2 (Nrf2) is a key transcription factor that is critical for cellular defense against oxidative and xenobiotic insults. Nrf2 heterodimerizes with small Maf (sMaf) proteins and binds to antioxidant response elements (AREs) to activate a battery of cytoprotective genes. However, it...
Autores principales: | Hirotsu, Yosuke, Katsuoka, Fumiki, Funayama, Ryo, Nagashima, Takeshi, Nishida, Yuichiro, Nakayama, Keiko, Douglas Engel, James, Yamamoto, Masayuki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488259/ https://www.ncbi.nlm.nih.gov/pubmed/22965115 http://dx.doi.org/10.1093/nar/gks827 |
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