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Dioxaphosphorinane-Constrained Nucleic Acid Dinucleotides as Tools for Structural Tuning of Nucleic Acids
We describe a rational approach devoted to modulate the sugar-phosphate backbone geometry of nucleic acids. Constraints were generated by connecting one oxygen of the phosphate group to a carbon of the sugar moiety. The so-called dioxaphosphorinane rings were introduced at key positions along the su...
Autores principales: | Catana, Dan-Andrei, Renard, Brice-Loïc, Maturano, Marie, Payrastre, Corinne, Tarrat, Nathalie, Escudier, Jean-Marc |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488415/ https://www.ncbi.nlm.nih.gov/pubmed/23150809 http://dx.doi.org/10.1155/2012/215876 |
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