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The persistent release of HMGB1 contributes to tactile hyperalgesia in a rodent model of neuropathic pain
BACKGROUND: High-mobility group box-1 protein (HMGB1) is a nuclear protein that regulates gene expression throughout the body. It can also become cytoplasmic and function as a neuromodulatory cytokine after tissue damage or injury. The manner in which HMGB1 influences the peripheral nervous system f...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488576/ https://www.ncbi.nlm.nih.gov/pubmed/22824385 http://dx.doi.org/10.1186/1742-2094-9-180 |