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Cancer specific promoter CpG Islands hypermethylation of HOP homeobox (HOPX) gene and its potential tumor suppressive role in pancreatic carcinogenesis

BACKGROUND: We have recently identified HOP hoemobox (HOPX) as a tumor suppressor gene candidate, characterized by tumor-specific promoter DNA hypermethylation in human cancers, and it can remarkably inhibit tumors’ aggressive phenotypes. In this current study, we for the first time examined methyla...

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Detalles Bibliográficos
Autores principales:	Waraya, Mina, Yamashita, Keishi, Katoh, Hiroshi, Ooki, Akira, Kawamata, Hiroshi, Nishimiya, Hiroshi, Nakamura, Kazunori, Ema, Akira, Watanabe, Masahiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488580/ https://www.ncbi.nlm.nih.gov/pubmed/22958219 http://dx.doi.org/10.1186/1471-2407-12-397

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