Changes in the Brain Accumulation of Glucocorticoids in abcb1a-Deficient CF-1 Mice

The multidrug resistance transporter, P-glycoprotein (P-gp), contributes to highly lipophilic molecules penetrating the brain from the blood at a much lower rate than expected, and has numerous substrates, inhibitors and modulators. The drug-transporting isoform of P-gp is coded by a single human ge...

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Detalles Bibliográficos
Autores principales: Mason, B L, Pariante, C M, Thomas, S A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488597/
https://www.ncbi.nlm.nih.gov/pubmed/22702373
http://dx.doi.org/10.1111/j.1365-2826.2012.02353.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488597/
https://www.ncbi.nlm.nih.gov/pubmed/22702373
http://dx.doi.org/10.1111/j.1365-2826.2012.02353.x

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