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Changes in the Brain Accumulation of Glucocorticoids in abcb1a-Deficient CF-1 Mice
The multidrug resistance transporter, P-glycoprotein (P-gp), contributes to highly lipophilic molecules penetrating the brain from the blood at a much lower rate than expected, and has numerous substrates, inhibitors and modulators. The drug-transporting isoform of P-gp is coded by a single human ge...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488597/ https://www.ncbi.nlm.nih.gov/pubmed/22702373 http://dx.doi.org/10.1111/j.1365-2826.2012.02353.x |