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Puromycin aminonucleoside modulates p130Cas of podocytes

PURPOSE: Puromycin aminonucleoside (PAN) specifically injures podocytes, leading to foot process effacement, actin cytoskeleton disorganization, and abnormal distribution of slit diaphragm proteins. p130Cas is a docking protein connecting F-actin fibers to the glomerular basement membrane (GBM) and...

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Detalles Bibliográficos
Autores principales: Ha, Tae-Sun, Choi, Ji-Young, Park, Hye-Young
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Pediatric Society 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488612/
https://www.ncbi.nlm.nih.gov/pubmed/23133483
http://dx.doi.org/10.3345/kjp.2012.55.10.371