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Design of potential siRNA molecules for T antigen gene silencing of Merkel Cell Polyomavirus

Merkel cell carcinoma (MCC) is the most aggressive skin cancer. Recently, it was demonstrated that human Merkel cell polyomavirus (MCV) is clonally integrated in 80% of MCC tumors. Genetic studies of MCV have shown that T antigen protein is responsible for replication of genome and play a foremost r...

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Detalles Bibliográficos
Autores principales: Hoque, Kazi Muhammad Ahasanul, Azim, Md Faisal, Mia, M Robin, Kayesh, Rafidin, Ali, Md Hazrat, Islam, Md Jahidul, Shakil, Shahriar Kabir, Shuvra, Tonmay Modak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488834/
https://www.ncbi.nlm.nih.gov/pubmed/23144552
http://dx.doi.org/10.6026/97320630008924