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Molecular docking and virtual screening for novel protein tyrosine phosphatase 1B (PTP1B) inhibitors
Protein tyrosine phosphatase 1B (PTP1B) functions as major negative regulator of insulin and leptin signaling pathways. In view of this, PTP1B is an significant target for drug development against cancer, diabetes and obesity. The aim of the current study is to identify PTP1B inhibitors by means of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Biomedical Informatics
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488847/ https://www.ncbi.nlm.nih.gov/pubmed/23139594 http://dx.doi.org/10.6026/97320630008834 |