Dysregulation of fragile X mental retardation protein and metabotropic glutamate receptor 5 in superior frontal cortex of individuals with autism: a postmortem brain study

BACKGROUND: Fragile X syndrome is caused by loss of function of the fragile X mental retardation 1 (FMR1) gene and shares multiple phenotypes with autism. We have previously found reduced expression of the protein product of FMR1 (FMRP) in vermis of adults with autism. METHODS: In the current study,...

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Detalles Bibliográficos
Autores principales: Fatemi, S Hossein, Folsom, Timothy D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3488976/
https://www.ncbi.nlm.nih.gov/pubmed/21548960
http://dx.doi.org/10.1186/2040-2392-2-6

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