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Multispectral imaging flow cytometry reveals distinct frequencies of γ-H2AX foci induction in DNA double strand break repair defective human cell lines

The measurement of γ-H2AX foci induction in cells provides a sensitive and reliable method for the quantitation of DNA damage responses in a variety of cell types. Accurate and rapid methods to conduct such observations are desirable. In this study, we have employed the novel technique of multispect...

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Detalles Bibliográficos
Autores principales: Bourton, Emma C, Plowman, Piers N, Zahir, Sheba Adam, Senguloglu, Gonul Ulus, Serrai, Hiba, Bottley, Graham, Parris, Christopher N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Subscription Services, Inc., A Wiley Company 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489045/
https://www.ncbi.nlm.nih.gov/pubmed/22170789
http://dx.doi.org/10.1002/cyto.a.21171