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GluN1 hypomorph mice exhibit wide-ranging behavioral alterations

The psychotomimetic effects of N-methyl-d-aspartate receptor (NMDA) antagonists such as ketamine and phencyclidine suggest a role for reduced NMDA receptor-mediated neurotransmission in schizophrenia. GluN1 ‘hypomorph’ (GluN1(hypo)) mice exhibit reduced NMDA receptor expression and have been suggest...

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Detalles Bibliográficos
Autores principales: Barkus, C, Dawson, L A, Sharp, T, Bannerman, D M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489048/
https://www.ncbi.nlm.nih.gov/pubmed/22300668
http://dx.doi.org/10.1111/j.1601-183X.2012.00767.x

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