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Computational validation of 3-ammonio-3-(4-oxido- 1H-imidazol-1-ium-5-yl) propane-1, 1-bis (olate) as a potent anti-tubercular drug against mt-MetAP

The advent of Multi Drug Resistant (MDR) strain of Mycobacterium tuberculosis (TB) necessitated search for new drug targets for the bacterium. It is reported that 3.3% of all new tuberculosis cases had multidrug resistance (MDR-TB) in 2009 and each year, about 0.44 million MDR-TB cases are estimated...

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Detalles Bibliográficos
Autores principales: Chowdhury, Abhishek, Sen, Shantanu, Dey, Pradip, Chetia, Pankaj, Talukdar, Anupam Das, Bhattacharjee, Amitabha, Choudhury, Manabendra Dutta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489093/
https://www.ncbi.nlm.nih.gov/pubmed/23144543
http://dx.doi.org/10.6026/97320630008875