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Materials from peptide assembly: towards the treatment of cancer and transmittable disease
As the prevalence of cancer and transmittable disease persists, the development of new and more advanced therapies remains a priority in medical research. An emerging platform for the treatment of these illnesses is the use of materials formed via peptide assembly where the bulk material itself acts...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489472/ https://www.ncbi.nlm.nih.gov/pubmed/21507707 http://dx.doi.org/10.1016/j.cbpa.2011.03.021 |
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author | Branco, Monica C Sigano, Dina M Schneider, Joel P |
author_facet | Branco, Monica C Sigano, Dina M Schneider, Joel P |
author_sort | Branco, Monica C |
collection | PubMed |
description | As the prevalence of cancer and transmittable disease persists, the development of new and more advanced therapies remains a priority in medical research. An emerging platform for the treatment of these illnesses is the use of materials formed via peptide assembly where the bulk material itself acts as the therapeutic. Higher ordered peptide structures with defined chemistry are capable of cellular targeting, recognition, and internalization. Recent design efforts are being made to exploit the nanoscale definition of the materials formed by assembling peptides to target cancer and microbial cells and to function as vaccines. This review focuses on assembled peptide materials that actively participate in the biological processes important to cancer and transmittable diseases to exert an anticipated functional outcome. |
format | Online Article Text |
id | pubmed-3489472 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-34894722012-11-05 Materials from peptide assembly: towards the treatment of cancer and transmittable disease Branco, Monica C Sigano, Dina M Schneider, Joel P Curr Opin Chem Biol Article As the prevalence of cancer and transmittable disease persists, the development of new and more advanced therapies remains a priority in medical research. An emerging platform for the treatment of these illnesses is the use of materials formed via peptide assembly where the bulk material itself acts as the therapeutic. Higher ordered peptide structures with defined chemistry are capable of cellular targeting, recognition, and internalization. Recent design efforts are being made to exploit the nanoscale definition of the materials formed by assembling peptides to target cancer and microbial cells and to function as vaccines. This review focuses on assembled peptide materials that actively participate in the biological processes important to cancer and transmittable diseases to exert an anticipated functional outcome. Elsevier 2011-06 2011-04-18 /pmc/articles/PMC3489472/ /pubmed/21507707 http://dx.doi.org/10.1016/j.cbpa.2011.03.021 Text en Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active. |
spellingShingle | Article Branco, Monica C Sigano, Dina M Schneider, Joel P Materials from peptide assembly: towards the treatment of cancer and transmittable disease |
title | Materials from peptide assembly: towards the treatment of cancer and transmittable disease |
title_full | Materials from peptide assembly: towards the treatment of cancer and transmittable disease |
title_fullStr | Materials from peptide assembly: towards the treatment of cancer and transmittable disease |
title_full_unstemmed | Materials from peptide assembly: towards the treatment of cancer and transmittable disease |
title_short | Materials from peptide assembly: towards the treatment of cancer and transmittable disease |
title_sort | materials from peptide assembly: towards the treatment of cancer and transmittable disease |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489472/ https://www.ncbi.nlm.nih.gov/pubmed/21507707 http://dx.doi.org/10.1016/j.cbpa.2011.03.021 |
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