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Materials from peptide assembly: towards the treatment of cancer and transmittable disease

As the prevalence of cancer and transmittable disease persists, the development of new and more advanced therapies remains a priority in medical research. An emerging platform for the treatment of these illnesses is the use of materials formed via peptide assembly where the bulk material itself acts...

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Detalles Bibliográficos
Autores principales: Branco, Monica C, Sigano, Dina M, Schneider, Joel P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489472/
https://www.ncbi.nlm.nih.gov/pubmed/21507707
http://dx.doi.org/10.1016/j.cbpa.2011.03.021
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author Branco, Monica C
Sigano, Dina M
Schneider, Joel P
author_facet Branco, Monica C
Sigano, Dina M
Schneider, Joel P
author_sort Branco, Monica C
collection PubMed
description As the prevalence of cancer and transmittable disease persists, the development of new and more advanced therapies remains a priority in medical research. An emerging platform for the treatment of these illnesses is the use of materials formed via peptide assembly where the bulk material itself acts as the therapeutic. Higher ordered peptide structures with defined chemistry are capable of cellular targeting, recognition, and internalization. Recent design efforts are being made to exploit the nanoscale definition of the materials formed by assembling peptides to target cancer and microbial cells and to function as vaccines. This review focuses on assembled peptide materials that actively participate in the biological processes important to cancer and transmittable diseases to exert an anticipated functional outcome.
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spelling pubmed-34894722012-11-05 Materials from peptide assembly: towards the treatment of cancer and transmittable disease Branco, Monica C Sigano, Dina M Schneider, Joel P Curr Opin Chem Biol Article As the prevalence of cancer and transmittable disease persists, the development of new and more advanced therapies remains a priority in medical research. An emerging platform for the treatment of these illnesses is the use of materials formed via peptide assembly where the bulk material itself acts as the therapeutic. Higher ordered peptide structures with defined chemistry are capable of cellular targeting, recognition, and internalization. Recent design efforts are being made to exploit the nanoscale definition of the materials formed by assembling peptides to target cancer and microbial cells and to function as vaccines. This review focuses on assembled peptide materials that actively participate in the biological processes important to cancer and transmittable diseases to exert an anticipated functional outcome. Elsevier 2011-06 2011-04-18 /pmc/articles/PMC3489472/ /pubmed/21507707 http://dx.doi.org/10.1016/j.cbpa.2011.03.021 Text en Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Article
Branco, Monica C
Sigano, Dina M
Schneider, Joel P
Materials from peptide assembly: towards the treatment of cancer and transmittable disease
title Materials from peptide assembly: towards the treatment of cancer and transmittable disease
title_full Materials from peptide assembly: towards the treatment of cancer and transmittable disease
title_fullStr Materials from peptide assembly: towards the treatment of cancer and transmittable disease
title_full_unstemmed Materials from peptide assembly: towards the treatment of cancer and transmittable disease
title_short Materials from peptide assembly: towards the treatment of cancer and transmittable disease
title_sort materials from peptide assembly: towards the treatment of cancer and transmittable disease
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489472/
https://www.ncbi.nlm.nih.gov/pubmed/21507707
http://dx.doi.org/10.1016/j.cbpa.2011.03.021
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