Optimization of de novo transcriptome assembly from high-throughput short read sequencing data improves functional annotation for non-model organisms

BACKGROUND: The k-mer hash length is a key factor affecting the output of de novo transcriptome assembly packages using de Bruijn graph algorithms. Assemblies constructed with varying single k-mer choices might result in the loss of unique contiguous sequences (contigs) and relevant biological infor...

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Detalles Bibliográficos
Autores principales: Haznedaroglu, Berat Z, Reeves, Darryl, Rismani-Yazdi, Hamid, Peccia, Jordan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489510/
https://www.ncbi.nlm.nih.gov/pubmed/22808927
http://dx.doi.org/10.1186/1471-2105-13-170

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