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A cross-validation scheme for machine learning algorithms in shotgun proteomics

Peptides are routinely identified from mass spectrometry-based proteomics experiments by matching observed spectra to peptides derived from protein databases. The error rates of these identifications can be estimated by target-decoy analysis, which involves matching spectra to shuffled or reversed p...

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Detalles Bibliográficos
Autores principales: Granholm, Viktor, Noble, William Stafford, Käll, Lukas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489528/
https://www.ncbi.nlm.nih.gov/pubmed/23176259
http://dx.doi.org/10.1186/1471-2105-13-S16-S3

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