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Normalization and missing value imputation for label-free LC-MS analysis
Shotgun proteomic data are affected by a variety of known and unknown systematic biases as well as high proportions of missing values. Typically, normalization is performed in an attempt to remove systematic biases from the data before statistical inference, sometimes followed by missing value imput...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489534/ https://www.ncbi.nlm.nih.gov/pubmed/23176322 http://dx.doi.org/10.1186/1471-2105-13-S16-S5 |