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Statistical protein quantification and significance analysis in label-free LC-MS experiments with complex designs
BACKGROUND: Liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS) is widely used for quantitative proteomic investigations. The typical output of such studies is a list of identified and quantified peptides. The biological and clinical interest is, however, usually focused on quanti...
Autores principales: | Clough, Timothy, Thaminy, Safia, Ragg, Susanne, Aebersold, Ruedi, Vitek, Olga |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489535/ https://www.ncbi.nlm.nih.gov/pubmed/23176351 http://dx.doi.org/10.1186/1471-2105-13-S16-S6 |
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