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Preserved vascular integrity and enhanced survival following neuropilin-1 inhibition in a mouse model of CD8 T cell-initiated CNS vascular permeability

BACKGROUND: Altered permeability of the blood–brain barrier (BBB) is a feature of numerous neurological conditions including multiple sclerosis, cerebral malaria, viral hemorrhagic fevers and acute hemorrhagic leukoencephalitis. Our laboratory has developed a murine model of CD8 T cell-initiated cen...

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Detalles Bibliográficos
Autores principales:	Suidan, Georgette L, Dickerson, Jonathan W, Johnson, Holly L, Chan, Theresa W, Pavelko, Kevin D, Pirko, Istvan, Seroogy, Kim B, Johnson, Aaron J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Short Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489603/ https://www.ncbi.nlm.nih.gov/pubmed/22985494 http://dx.doi.org/10.1186/1742-2094-9-218

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