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Increased tumorigenesis associated with loss of the tumor suppressor gene Cadm1
BACKGROUND: CADM1 encodes an immunoglobulin superfamily (IGSF) cell adhesion molecule. Inactivation of CADM1, either by promoter hypermethylation or loss of heterozygosity, has been reported in a wide variety of tumor types, thus it has been postulated as a tumor suppressor gene. FINDINGS: We show f...
Autores principales: | van der Weyden, Louise, Arends, Mark J, Rust, Alistair G, Poulogiannis, George, McIntyre, Rebecca E, Adams, David J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489691/ https://www.ncbi.nlm.nih.gov/pubmed/22553910 http://dx.doi.org/10.1186/1476-4598-11-29 |
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