Increased human Ca(2+)-activated Cl(-) channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients

BACKGROUND: The mechanisms underlying the association between smoking and mucus overproduction remain unknown. Because of its involvement in other airway diseases, such as asthma, we hypothesized that Ca(2+)-activated Cl(-) channel 1 (CLCA1) was associated with overproduction of mucus in the airways...

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Detalles Bibliográficos
Autores principales: Iwashita, Hiroki, Fujimoto, Keisaku, Morita, Shigeru, Nakanishi, Atsushi, Kubo, Keishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489697/
https://www.ncbi.nlm.nih.gov/pubmed/22731784
http://dx.doi.org/10.1186/1465-9921-13-55

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489697/
https://www.ncbi.nlm.nih.gov/pubmed/22731784
http://dx.doi.org/10.1186/1465-9921-13-55

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