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Increased human Ca(2+)-activated Cl(-) channel 1 expression and mucus overproduction in airway epithelia of smokers and chronic obstructive pulmonary disease patients
BACKGROUND: The mechanisms underlying the association between smoking and mucus overproduction remain unknown. Because of its involvement in other airway diseases, such as asthma, we hypothesized that Ca(2+)-activated Cl(-) channel 1 (CLCA1) was associated with overproduction of mucus in the airways...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489697/ https://www.ncbi.nlm.nih.gov/pubmed/22731784 http://dx.doi.org/10.1186/1465-9921-13-55 |