Particulate matter air pollution disrupts endothelial cell barrier via calpain-mediated tight junction protein degradation

BACKGROUND: Exposure to particulate matter (PM) is a significant risk factor for increased cardiopulmonary morbidity and mortality. The mechanism of PM-mediated pathophysiology remains unknown. However, PM is proinflammatory to the endothelium and increases vascular permeability in vitro and in vivo...

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Detalles Bibliográficos
Autores principales: Wang, Ting, Wang, Lichun, Moreno-Vinasco, Liliana, Lang, Gabriel D, Siegler, Jessica H, Mathew, Biji, Usatyuk, Peter V, Samet, Jonathan M, Geyh, Alison S, Breysse, Patrick N, Natarajan, Viswanathan, Garcia, Joe G N
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489700/
https://www.ncbi.nlm.nih.gov/pubmed/22931549
http://dx.doi.org/10.1186/1743-8977-9-35

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