L-Carnitine Is an Endogenous HDAC Inhibitor Selectively Inhibiting Cancer Cell Growth In Vivo and In Vitro

L-carnitine (LC) is generally believed to transport long-chain acyl groups from fatty acids into the mitochondrial matrix for ATP generation via the citric acid cycle. Based on Warburg's theory that most cancer cells mainly depend on glycolysis for ATP generation, we hypothesize that, LC treatm...

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Detalles Bibliográficos
Autores principales: Huang, Hongbiao, Liu, Ningning, Guo, Haiping, Liao, Siyan, Li, Xiaofen, Yang, Changshan, Liu, Shouting, Song, Wenbin, Liu, Chunjiao, Guan, Lixia, Li, Bing, Xu, Li, Zhang, Change, Wang, Xuejun, Dou, Q. Ping, Liu, Jinbao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489732/
https://www.ncbi.nlm.nih.gov/pubmed/23139833
http://dx.doi.org/10.1371/journal.pone.0049062

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489732/
https://www.ncbi.nlm.nih.gov/pubmed/23139833
http://dx.doi.org/10.1371/journal.pone.0049062

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