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L-Carnitine Is an Endogenous HDAC Inhibitor Selectively Inhibiting Cancer Cell Growth In Vivo and In Vitro
L-carnitine (LC) is generally believed to transport long-chain acyl groups from fatty acids into the mitochondrial matrix for ATP generation via the citric acid cycle. Based on Warburg's theory that most cancer cells mainly depend on glycolysis for ATP generation, we hypothesize that, LC treatm...
Autores principales: | Huang, Hongbiao, Liu, Ningning, Guo, Haiping, Liao, Siyan, Li, Xiaofen, Yang, Changshan, Liu, Shouting, Song, Wenbin, Liu, Chunjiao, Guan, Lixia, Li, Bing, Xu, Li, Zhang, Change, Wang, Xuejun, Dou, Q. Ping, Liu, Jinbao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489732/ https://www.ncbi.nlm.nih.gov/pubmed/23139833 http://dx.doi.org/10.1371/journal.pone.0049062 |
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