TAMable tumor-associated macrophages in response to innate RNA sensing

Antitumor effect of PolyI:C (a viral dsRNA analog) has been attributed to dendritic cell (DC)-maturation activity, that drives antitumor NK cells, DC cross-presentation, cytotoxic T lymphocytes and many IFN-inducible genes. According to a recent paper, tumor-infiltrating M2 macrophages are found to...

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Detalles Bibliográficos
Autores principales: Seya, Tsukasa, Shime, Hiroaki, Matsumoto, Misako
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489733/
https://www.ncbi.nlm.nih.gov/pubmed/23162785
http://dx.doi.org/10.4161/onci.19894
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author Seya, Tsukasa
Shime, Hiroaki
Matsumoto, Misako
author_facet Seya, Tsukasa
Shime, Hiroaki
Matsumoto, Misako
author_sort Seya, Tsukasa
collection PubMed
description Antitumor effect of PolyI:C (a viral dsRNA analog) has been attributed to dendritic cell (DC)-maturation activity, that drives antitumor NK cells, DC cross-presentation, cytotoxic T lymphocytes and many IFN-inducible genes. According to a recent paper, tumor-infiltrating M2 macrophages are found to become an additional antitumor effector through polyI:C response.
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spelling pubmed-34897332012-11-16 TAMable tumor-associated macrophages in response to innate RNA sensing Seya, Tsukasa Shime, Hiroaki Matsumoto, Misako Oncoimmunology Author's View Antitumor effect of PolyI:C (a viral dsRNA analog) has been attributed to dendritic cell (DC)-maturation activity, that drives antitumor NK cells, DC cross-presentation, cytotoxic T lymphocytes and many IFN-inducible genes. According to a recent paper, tumor-infiltrating M2 macrophages are found to become an additional antitumor effector through polyI:C response. Landes Bioscience 2012-09-01 /pmc/articles/PMC3489733/ /pubmed/23162785 http://dx.doi.org/10.4161/onci.19894 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Seya, Tsukasa
Shime, Hiroaki
Matsumoto, Misako
TAMable tumor-associated macrophages in response to innate RNA sensing
title TAMable tumor-associated macrophages in response to innate RNA sensing
title_full TAMable tumor-associated macrophages in response to innate RNA sensing
title_fullStr TAMable tumor-associated macrophages in response to innate RNA sensing
title_full_unstemmed TAMable tumor-associated macrophages in response to innate RNA sensing
title_short TAMable tumor-associated macrophages in response to innate RNA sensing
title_sort tamable tumor-associated macrophages in response to innate rna sensing
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489733/
https://www.ncbi.nlm.nih.gov/pubmed/23162785
http://dx.doi.org/10.4161/onci.19894
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