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TAMable tumor-associated macrophages in response to innate RNA sensing

Antitumor effect of PolyI:C (a viral dsRNA analog) has been attributed to dendritic cell (DC)-maturation activity, that drives antitumor NK cells, DC cross-presentation, cytotoxic T lymphocytes and many IFN-inducible genes. According to a recent paper, tumor-infiltrating M2 macrophages are found to...

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Detalles Bibliográficos
Autores principales:	Seya, Tsukasa, Shime, Hiroaki, Matsumoto, Misako
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489733/ https://www.ncbi.nlm.nih.gov/pubmed/23162785 http://dx.doi.org/10.4161/onci.19894

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