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An ENU mutagenesis approach to dissect “self”-induced immune responses: Unraveling the genetic footprint of immunosurveillance
The immune system exerts a critical function as it recognizes and eliminates transformed or neoplastic cells, a process also referred to as immunosurveillance. NK cells play a particularly important role in that they are able to recognize tumor cells via “missing-self”—i.e., the absence of major his...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Landes Bioscience
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489741/ https://www.ncbi.nlm.nih.gov/pubmed/23162753 http://dx.doi.org/10.4161/onci.20580 |