DNA methylation markers for breast cancer prognosis: Unmasking the immune component

Currently, most of the prognostic and predictive gene expression signatures emerging for breast cancer concern the tumor component. In Dedeurwaerder et al. we show that DNA methylation profiling of breast tumors is a particularly sensitive means of capturing features of the immune component of breas...

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Detalles Bibliográficos
Autores principales: Dedeurwaerder, Sarah, Fuks, François
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Author's View
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489760/
https://www.ncbi.nlm.nih.gov/pubmed/23162772
http://dx.doi.org/10.4161/onci.19996
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author Dedeurwaerder, Sarah
Fuks, François
author_facet Dedeurwaerder, Sarah
Fuks, François
author_sort Dedeurwaerder, Sarah
collection PubMed
description Currently, most of the prognostic and predictive gene expression signatures emerging for breast cancer concern the tumor component. In Dedeurwaerder et al. we show that DNA methylation profiling of breast tumors is a particularly sensitive means of capturing features of the immune component of breast tumors. Most importantly, correlation is observed between T-cell marker genes and breast cancer clinical outcome.
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spelling pubmed-34897602012-11-16 DNA methylation markers for breast cancer prognosis: Unmasking the immune component Dedeurwaerder, Sarah Fuks, François Oncoimmunology Author's View Currently, most of the prognostic and predictive gene expression signatures emerging for breast cancer concern the tumor component. In Dedeurwaerder et al. we show that DNA methylation profiling of breast tumors is a particularly sensitive means of capturing features of the immune component of breast tumors. Most importantly, correlation is observed between T-cell marker genes and breast cancer clinical outcome. Landes Bioscience 2012-09-01 /pmc/articles/PMC3489760/ /pubmed/23162772 http://dx.doi.org/10.4161/onci.19996 Text en Copyright © 2012 Landes Bioscience http://creativecommons.org/licenses/by-nc/3.0/ This is an open-access article licensed under a Creative Commons Attribution-NonCommercial 3.0 Unported License. The article may be redistributed, reproduced, and reused for non-commercial purposes, provided the original source is properly cited.
spellingShingle Author's View
Dedeurwaerder, Sarah
Fuks, François
DNA methylation markers for breast cancer prognosis: Unmasking the immune component
title DNA methylation markers for breast cancer prognosis: Unmasking the immune component
title_full DNA methylation markers for breast cancer prognosis: Unmasking the immune component
title_fullStr DNA methylation markers for breast cancer prognosis: Unmasking the immune component
title_full_unstemmed DNA methylation markers for breast cancer prognosis: Unmasking the immune component
title_short DNA methylation markers for breast cancer prognosis: Unmasking the immune component
title_sort dna methylation markers for breast cancer prognosis: unmasking the immune component
topic Author's View
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489760/
https://www.ncbi.nlm.nih.gov/pubmed/23162772
http://dx.doi.org/10.4161/onci.19996
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