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The role of SMAC mimetics in regulation of tumor cell death and immunity

Mimetics of second mitochondria-derived activator of caspases (SMAC) enhance tumor cell death in a variety of cancers. Several molecular mechanisms of action have been identified. However, it was only recently that the modus of action was linked to stimulation of anti-tumor immunity. Here we comment...

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Detalles Bibliográficos
Autores principales:	Emeagi, Perpetua U., Thielemans, Kris, Breckpot, Karine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Landes Bioscience 2012
Materias:	Author's View
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489761/ https://www.ncbi.nlm.nih.gov/pubmed/23162773 http://dx.doi.org/10.4161/onci.20369

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