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Won’t you come on in? How to favor lymphocyte infiltration in tumors
Abnormal tumor vasculature and endothelial cell anergy limit tumor/T-cell interactions. We have found that NGR-TNF, a tumor vasculature-homing derivative of TNF, selectively activates endothelial cells in neoplastic tissues and induces the release of chemokines that favor tumor infiltration by T cel...
Autores principales: | Bellone, Matteo, Calcinotto, Arianna, Corti, Angelo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Landes Bioscience
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489769/ https://www.ncbi.nlm.nih.gov/pubmed/23162781 http://dx.doi.org/10.4161/onci.20213 |
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