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Won’t you come on in? How to favor lymphocyte infiltration in tumors

Abnormal tumor vasculature and endothelial cell anergy limit tumor/T-cell interactions. We have found that NGR-TNF, a tumor vasculature-homing derivative of TNF, selectively activates endothelial cells in neoplastic tissues and induces the release of chemokines that favor tumor infiltration by T cel...

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Detalles Bibliográficos
Autores principales: Bellone, Matteo, Calcinotto, Arianna, Corti, Angelo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3489769/
https://www.ncbi.nlm.nih.gov/pubmed/23162781
http://dx.doi.org/10.4161/onci.20213

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